node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppro_0283 | Ppro_1413 | Ppro_0283 | Ppro_1413 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. | 0.999 |
Ppro_0283 | Ppro_2543 | Ppro_0283 | Ppro_2543 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | L-fuculose 1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; KEGG: pca:Pcar_3030 L-fuculose phosphate aldolase. | 0.712 |
Ppro_0283 | mtnA | Ppro_0283 | Ppro_0510 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.824 |
Ppro_0507 | Ppro_0508 | Ppro_0507 | Ppro_0508 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | 0.969 |
Ppro_0507 | Ppro_0509 | Ppro_0507 | Ppro_0509 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | 0.773 |
Ppro_0507 | glnE | Ppro_0507 | Ppro_0511 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.556 |
Ppro_0507 | mtnA | Ppro_0507 | Ppro_0510 | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.524 |
Ppro_0508 | Ppro_0507 | Ppro_0508 | Ppro_0507 | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | 0.969 |
Ppro_0508 | Ppro_0509 | Ppro_0508 | Ppro_0509 | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | 0.773 |
Ppro_0508 | glnE | Ppro_0508 | Ppro_0511 | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.539 |
Ppro_0508 | mtnA | Ppro_0508 | Ppro_0510 | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.524 |
Ppro_0509 | Ppro_0507 | Ppro_0509 | Ppro_0507 | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU1879 DNA-binding response regulator. | 0.773 |
Ppro_0509 | Ppro_0508 | Ppro_0509 | Ppro_0508 | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: gme:Gmet_1292 histidine kinase. | 0.773 |
Ppro_0509 | glnE | Ppro_0509 | Ppro_0511 | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.524 |
Ppro_0509 | mtnA | Ppro_0509 | Ppro_0510 | SMART: helicase c2; DEAD-like helicases-like; KEGG: gme:Gmet_3167 helicase C2. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.541 |
Ppro_1413 | Ppro_0283 | Ppro_1413 | Ppro_0283 | Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 0.999 |
Ppro_1413 | Ppro_2543 | Ppro_1413 | Ppro_2543 | Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. | L-fuculose 1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; KEGG: pca:Pcar_3030 L-fuculose phosphate aldolase. | 0.622 |
Ppro_1413 | mtnA | Ppro_1413 | Ppro_0510 | Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.822 |
Ppro_2543 | Ppro_0283 | Ppro_2543 | Ppro_0283 | L-fuculose 1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; KEGG: pca:Pcar_3030 L-fuculose phosphate aldolase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: gme:Gmet_0504 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 0.712 |
Ppro_2543 | Ppro_1413 | Ppro_2543 | Ppro_1413 | L-fuculose 1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; KEGG: pca:Pcar_3030 L-fuculose phosphate aldolase. | Methionine synthase (B12-dependent); PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein; KEGG: gme:Gmet_0549 homocysteine S-methyltransferase. | 0.622 |