STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (394 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
Ppro_2482
KEGG: ade:Adeh_2933 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 0.991
Ppro_1026
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; KEGG: pca:Pcar_0345 dehydrogenase complex E2 component, dihydrolipamide acetyltransferase.
  
 0.990
Ppro_2481
Succinate dehydrogenase subunit B; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: gme:Gmet_2395 succinate dehydrogenase.
  
 0.989
Ppro_1134
PFAM: Citrate synthase; KEGG: sth:STH2542 citrate synthase; Belongs to the citrate synthase family.
  
 
 0.971
Ppro_2323
2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gsu:GSU1470 keto/oxoacid ferredoxin oxidoreductase, gamma subunit.
 
 
 0.957
Ppro_2325
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gme:Gmet_1362 2-oxoglutarate ferredoxin oxidoreductase.
 
 
 0.956
Ppro_0298
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: gsu:GSU0097 pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.953
Ppro_0549
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1164 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.951
Ppro_2324
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: gme:Gmet_1363 ferrodoxin oxidoreductase beta subunit.
  
 
 0.942
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.