node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppro_1717 | Ppro_1789 | Ppro_1717 | Ppro_1789 | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | 0.471 |
Ppro_1717 | Ppro_2261 | Ppro_1717 | Ppro_2261 | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | 0.987 |
Ppro_1717 | pheT | Ppro_1717 | Ppro_2303 | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | KEGG: gme:Gmet_1416 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.465 |
Ppro_1717 | tsaD | Ppro_1717 | Ppro_2493 | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.971 |
Ppro_1789 | Ppro_1717 | Ppro_1789 | Ppro_1717 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | 0.471 |
Ppro_1789 | Ppro_2261 | Ppro_1789 | Ppro_2261 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | 0.534 |
Ppro_1789 | rsmA | Ppro_1789 | Ppro_2492 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.586 |
Ppro_1789 | topA | Ppro_1789 | Ppro_0528 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.422 |
Ppro_1789 | tsaD | Ppro_1789 | Ppro_2493 | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.742 |
Ppro_2261 | Ppro_1717 | Ppro_2261 | Ppro_1717 | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | PFAM: peptidase M22, glycoprotease; KEGG: gme:Gmet_1258 peptidase M22, glycoprotease. | 0.987 |
Ppro_2261 | Ppro_1789 | Ppro_2261 | Ppro_1789 | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: gme:Gmet_1595 SUA5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | 0.534 |
Ppro_2261 | pheT | Ppro_2261 | Ppro_2303 | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | KEGG: gme:Gmet_1416 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.491 |
Ppro_2261 | tsaD | Ppro_2261 | Ppro_2493 | PFAM: protein of unknown function UPF0079; KEGG: gme:Gmet_1881 hypothetical protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.944 |
Ppro_2494 | Ppro_2495 | Ppro_2494 | Ppro_2495 | PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: gsu:GSU1866 PhoH family protein. | TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: gme:Gmet_1300 cysteine desulphurase related, unknown function. | 0.636 |
Ppro_2494 | rsmA | Ppro_2494 | Ppro_2492 | PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: gsu:GSU1866 PhoH family protein. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.711 |
Ppro_2494 | tsaD | Ppro_2494 | Ppro_2493 | PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: gsu:GSU1866 PhoH family protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.716 |
Ppro_2495 | Ppro_2494 | Ppro_2495 | Ppro_2494 | TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: gme:Gmet_1300 cysteine desulphurase related, unknown function. | PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: gsu:GSU1866 PhoH family protein. | 0.636 |
Ppro_2495 | rsmA | Ppro_2495 | Ppro_2492 | TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: gme:Gmet_1300 cysteine desulphurase related, unknown function. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.686 |
Ppro_2495 | tsaD | Ppro_2495 | Ppro_2493 | TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; KEGG: gme:Gmet_1300 cysteine desulphurase related, unknown function. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.634 |
aroB | topA | Ppro_2027 | Ppro_0528 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.735 |