node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppro_2673 | Ppro_2674 | Ppro_2673 | Ppro_2674 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | KEGG: gme:Gmet_0742 hypothetical protein. | 0.535 |
Ppro_2673 | Ppro_3437 | Ppro_2673 | Ppro_3437 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: gsu:GSU0421 flagellar motor switch protein FliM. | 0.705 |
Ppro_2673 | aspS | Ppro_2673 | Ppro_2329 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.710 |
Ppro_2673 | lepA | Ppro_2673 | Ppro_2331 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.514 |
Ppro_2673 | rplS | Ppro_2673 | Ppro_1093 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.692 |
Ppro_2673 | rpmF | Ppro_2673 | Ppro_1740 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: gme:Gmet_1597 ribosomal protein S32; Belongs to the bacterial ribosomal protein bL32 family. | 0.610 |
Ppro_2673 | ruvA | Ppro_2673 | Ppro_2671 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.742 |
Ppro_2673 | ruvC | Ppro_2673 | Ppro_2672 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.729 |
Ppro_2673 | tig | Ppro_2673 | Ppro_1184 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.614 |
Ppro_2673 | tsf | Ppro_2673 | Ppro_2045 | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.594 |
Ppro_2674 | Ppro_2673 | Ppro_2674 | Ppro_2673 | KEGG: gme:Gmet_0742 hypothetical protein. | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | 0.535 |
Ppro_2674 | ruvA | Ppro_2674 | Ppro_2671 | KEGG: gme:Gmet_0742 hypothetical protein. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.400 |
Ppro_2674 | ruvC | Ppro_2674 | Ppro_2672 | KEGG: gme:Gmet_0742 hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.400 |
Ppro_3437 | Ppro_2673 | Ppro_3437 | Ppro_2673 | PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: gsu:GSU0421 flagellar motor switch protein FliM. | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | 0.705 |
aspS | Ppro_2673 | Ppro_2329 | Ppro_2673 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | 0.710 |
aspS | lepA | Ppro_2329 | Ppro_2331 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.761 |
aspS | rpmF | Ppro_2329 | Ppro_1740 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: gme:Gmet_1597 ribosomal protein S32; Belongs to the bacterial ribosomal protein bL32 family. | 0.535 |
aspS | tig | Ppro_2329 | Ppro_1184 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.534 |
aspS | tsf | Ppro_2329 | Ppro_2045 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.567 |
lepA | Ppro_2673 | Ppro_2331 | Ppro_2673 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | PFAM: protein of unknown function DUF28; KEGG: gsu:GSU1074 hypothetical protein. | 0.514 |