STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (322 aa)    
Predicted Functional Partners:
Ppro_0014
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.991
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.953
Ppro_1261
Protoporphyrin IX magnesium-chelatase; KEGG: cte:CT0420 magnesium-chelatase, subunit D/I family; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; SMART: AAA ATPase.
  
 
 0.944
Ppro_2084
Protoporphyrin IX magnesium-chelatase; KEGG: cte:CT0420 magnesium-chelatase, subunit D/I family; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 
 0.944
Ppro_2942
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_0015 radical SAM.
  
 
 0.921
Ppro_1262
Protoporphyrin IX magnesium-chelatase; KEGG: cte:CT0421 magnesium-chelatase, subunit I family; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase.
   
 
 0.911
Ppro_2083
Protoporphyrin IX magnesium-chelatase; KEGG: mja:MJ0911 magnesium-chelatase subunit; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase.
   
 
 0.911
Ppro_1430
PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: mbu:Mbur_0957 uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family.
  
  
 0.783
Ppro_2101
UDP-galactopyranose mutase; PFAM: amine oxidase; KEGG: gsu:GSU1512 amine oxidase, flavin-containing.
  
  
 0.765
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.753
Your Current Organism:
Pelobacter propionicus
NCBI taxonomy Id: 338966
Other names: P. propionicus DSM 2379, Pelobacter propionicus DSM 2379, Pelobacter propionicus str. DSM 2379, Pelobacter propionicus strain DSM 2379
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