node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rfer_0002 | Rfer_1377 | Rfer_0002 | Rfer_1377 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.714 |
Rfer_0002 | Rfer_2197 | Rfer_0002 | Rfer_2197 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.681 |
Rfer_0002 | Rfer_3011 | Rfer_0002 | Rfer_3011 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.681 |
Rfer_0002 | Rfer_3347 | Rfer_0002 | Rfer_3347 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.721 |
Rfer_0002 | dut | Rfer_0002 | Rfer_2646 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.887 |
Rfer_1376 | Rfer_1377 | Rfer_1376 | Rfer_1377 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | 0.668 |
Rfer_1376 | Rfer_1378 | Rfer_1376 | Rfer_1378 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.658 |
Rfer_1376 | Rfer_1379 | Rfer_1376 | Rfer_1379 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | Phosphoribosyltransferase. | 0.647 |
Rfer_1376 | Rfer_1381 | Rfer_1376 | Rfer_1381 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | Dihydroorotase. | 0.577 |
Rfer_1376 | pyrB | Rfer_1376 | Rfer_1380 | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.632 |
Rfer_1377 | Rfer_0002 | Rfer_1377 | Rfer_0002 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.714 |
Rfer_1377 | Rfer_1376 | Rfer_1377 | Rfer_1376 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Deoxyribodipyrimidine photo-lyase type I; Belongs to the DNA photolyase family. | 0.668 |
Rfer_1377 | Rfer_1378 | Rfer_1377 | Rfer_1378 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.954 |
Rfer_1377 | Rfer_1379 | Rfer_1377 | Rfer_1379 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Phosphoribosyltransferase. | 0.840 |
Rfer_1377 | Rfer_1381 | Rfer_1377 | Rfer_1381 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Dihydroorotase. | 0.843 |
Rfer_1377 | Rfer_2197 | Rfer_1377 | Rfer_2197 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.940 |
Rfer_1377 | Rfer_3011 | Rfer_1377 | Rfer_3011 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.940 |
Rfer_1377 | Rfer_3347 | Rfer_1377 | Rfer_3347 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.940 |
Rfer_1377 | dut | Rfer_1377 | Rfer_2646 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.623 |
Rfer_1377 | pyrB | Rfer_1377 | Rfer_1380 | Protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.865 |