node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rfer_2463 | Rfer_2465 | Rfer_2463 | Rfer_2465 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Thiamine biosynthesis protein ThiS. | 0.786 |
Rfer_2463 | Rfer_2467 | Rfer_2463 | Rfer_2467 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Thiamine-phosphate diphosphorylase. | 0.777 |
Rfer_2463 | Rfer_2470 | Rfer_2463 | Rfer_2470 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Phosphomethylpyrimidine kinase. | 0.528 |
Rfer_2463 | thiE | Rfer_2463 | Rfer_2471 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.454 |
Rfer_2463 | thiG | Rfer_2463 | Rfer_2466 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.688 |
Rfer_2463 | thiM | Rfer_2463 | Rfer_2472 | Permease for cytosine/purines, uracil, thiamine, allantoin. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.490 |
Rfer_2465 | Rfer_2463 | Rfer_2465 | Rfer_2463 | Thiamine biosynthesis protein ThiS. | Permease for cytosine/purines, uracil, thiamine, allantoin. | 0.786 |
Rfer_2465 | Rfer_2467 | Rfer_2465 | Rfer_2467 | Thiamine biosynthesis protein ThiS. | Thiamine-phosphate diphosphorylase. | 0.952 |
Rfer_2465 | Rfer_2470 | Rfer_2465 | Rfer_2470 | Thiamine biosynthesis protein ThiS. | Phosphomethylpyrimidine kinase. | 0.794 |
Rfer_2465 | thiC | Rfer_2465 | Rfer_1708 | Thiamine biosynthesis protein ThiS. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.819 |
Rfer_2465 | thiE | Rfer_2465 | Rfer_2471 | Thiamine biosynthesis protein ThiS. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.666 |
Rfer_2465 | thiG | Rfer_2465 | Rfer_2466 | Thiamine biosynthesis protein ThiS. | Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.994 |
Rfer_2465 | thiM | Rfer_2465 | Rfer_2472 | Thiamine biosynthesis protein ThiS. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.489 |
Rfer_2467 | Rfer_2463 | Rfer_2467 | Rfer_2463 | Thiamine-phosphate diphosphorylase. | Permease for cytosine/purines, uracil, thiamine, allantoin. | 0.777 |
Rfer_2467 | Rfer_2465 | Rfer_2467 | Rfer_2465 | Thiamine-phosphate diphosphorylase. | Thiamine biosynthesis protein ThiS. | 0.952 |
Rfer_2467 | Rfer_2470 | Rfer_2467 | Rfer_2470 | Thiamine-phosphate diphosphorylase. | Phosphomethylpyrimidine kinase. | 0.999 |
Rfer_2467 | Rfer_2666 | Rfer_2467 | Rfer_2666 | Thiamine-phosphate diphosphorylase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.511 |
Rfer_2467 | Rfer_3398 | Rfer_2467 | Rfer_3398 | Thiamine-phosphate diphosphorylase. | Periplasmic sensor hybrid histidine kinase. | 0.550 |
Rfer_2467 | thiC | Rfer_2467 | Rfer_1708 | Thiamine-phosphate diphosphorylase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.885 |
Rfer_2467 | thiE | Rfer_2467 | Rfer_2471 | Thiamine-phosphate diphosphorylase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.924 |