STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltFLytic transglycosylase catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (483 aa)    
Predicted Functional Partners:
Asuc_0251
PFAM: MucB/RseB family protein; KEGG: pmu:PM1787 sigma-E factor regulatory protein.
  
     0.597
nudJ
PFAM: NUDIX hydrolase; KEGG: msu:MS2341 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
     0.578
Asuc_1186
PFAM: Methyltransferase type 11; KEGG: pmu:PM0686 hypothetical E.coli.
  
    0.542
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.530
priB
Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
 
     0.479
Asuc_1700
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: msu:MS1039 LysR protein; Belongs to the LysR transcriptional regulatory family.
  
     0.474
Asuc_0354
PFAM: protein of unknown function DUF513 hemX; KEGG: msu:MS0274 uncharacterized BCR.
  
     0.450
Asuc_0353
TIGRFAM: HemY protein; PFAM: HemY domain protein; KEGG: pmu:PM1815 hemY protein.
  
   
 0.447
Asuc_1076
PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: msu:MS2311 SH3 domain protein.
  
     0.404
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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