STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_07997AB hydrolase-1 domain-containing protein. (411 aa)    
Predicted Functional Partners:
HCAG_05764
NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial; Belongs to the complex I 30 kDa subunit family.
   
 0.787
HCAG_04623
NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family.
   
 0.770
HCAG_05509
NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial.
   
 0.769
HCAG_01733
NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 0.766
HCAG_03991
NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family.
   
 0.757
HCAG_00943
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.752
HCAG_03523
Uncharacterized protein; Belongs to the complex I LYR family.
   
 0.743
HCAG_01603
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
   
 0.735
HCAG_04359
Uncharacterized protein.
   
 0.734
HCAG_05081
L51_S25_CI-B8 domain-containing protein.
   
 0.734
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
Server load: low (14%) [HD]