STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_08644DNA topoisomerase 2. (1808 aa)    
Predicted Functional Partners:
HCAG_04798
TOPEUc domain-containing protein.
   
 
 0.960
HCAG_07829
Structural maintenance of chromosomes protein.
   
 
 0.898
HCAG_01770
Ubiquitin-like domain-containing protein.
    
 0.805
HCAG_03544
SMC_N domain-containing protein.
   
 
 0.803
HCAG_05621
Ubiquitin-conjugating enzyme E2-18 kDa; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.797
HCAG_08818
Structural maintenance of chromosomes protein.
   
 
 0.792
HCAG_06412
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
   
 
 0.791
HCAG_05203
Ubiquitin-conjugating enzyme E2-20 kDa; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.738
HCAG_07966
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.730
HCAG_04837
Uncharacterized protein.
   
  
 0.721
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.