STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPYACarboxypeptidase Y homolog A; Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity). (545 aa)    
Predicted Functional Partners:
VPS10
Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10 family.
      
 0.555
HCAG_01881
Uncharacterized protein.
   
 
 0.499
HCAG_05953
Tryptophan synthase.
     
 0.476
HCAG_09312
PRKCSH domain-containing protein.
   
 
 0.457
HCAG_00037
Vacuolar protease A; Belongs to the peptidase A1 family.
   
 0.430
HCAG_05605
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.430
HCAG_02770
Uncharacterized protein.
    
 
 0.424
HCAG_06419
Uncharacterized protein.
   
 0.417
HCAG_08665
Uncharacterized protein.
 
      0.407
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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