HCAG_02627 protein (Histoplasma capsulatum NAm1)

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Score

HCAG_02627

DNA ligase. (972 aa)

Predicted Functional Partners:

HCAG_02950

0.983

HCAG_05324

0.980

HCAG_00408

0.920

HCAG_03412

0.833

HCAG_05461

0.803

HCAG_08094

0.803

HCAG_02527

0.780

HCAG_05612

0.779

HCAG_03555

0.777

FEN1

0.776

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	HCAG_00408	A6QV55	A6QSQ2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_LIGASE_A3 domain-containing protein.	0.882
FEN1	HCAG_02627	A6QV55	A6QZ20	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.776
FEN1	HCAG_02950	A6QV55	A6QZZ3	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Ku domain-containing protein.	0.724
FEN1	HCAG_03412	A6QV55	A6R1A5	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	BRCT domain-containing protein.	0.854
FEN1	HCAG_03555	A6QV55	A6R1P7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.877
FEN1	HCAG_05324	A6QV55	A6R6R6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Ku domain-containing protein.	0.651
FEN1	HCAG_05612	A6QV55	A6R7K4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.893
HCAG_00408	FEN1	A6QSQ2	A6QV55	DNA_LIGASE_A3 domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.882
HCAG_00408	HCAG_02627	A6QSQ2	A6QZ20	DNA_LIGASE_A3 domain-containing protein.	DNA ligase.	0.920
HCAG_00408	HCAG_02950	A6QSQ2	A6QZZ3	DNA_LIGASE_A3 domain-containing protein.	Ku domain-containing protein.	0.780
HCAG_00408	HCAG_03412	A6QSQ2	A6R1A5	DNA_LIGASE_A3 domain-containing protein.	BRCT domain-containing protein.	0.604
HCAG_00408	HCAG_03555	A6QSQ2	A6R1P7	DNA_LIGASE_A3 domain-containing protein.	Uncharacterized protein.	0.704
HCAG_00408	HCAG_05324	A6QSQ2	A6R6R6	DNA_LIGASE_A3 domain-containing protein.	Ku domain-containing protein.	0.808
HCAG_00408	HCAG_05461	A6QSQ2	A6R753	DNA_LIGASE_A3 domain-containing protein.	HRDC domain-containing protein.	0.470
HCAG_00408	HCAG_08094	A6QSQ2	A6REM9	DNA_LIGASE_A3 domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.470
HCAG_02527	HCAG_02627	A6QYS0	A6QZ20	Peptidase_S24 domain-containing protein.	DNA ligase.	0.780
HCAG_02527	HCAG_02950	A6QYS0	A6QZZ3	Peptidase_S24 domain-containing protein.	Ku domain-containing protein.	0.763
HCAG_02527	HCAG_05324	A6QYS0	A6R6R6	Peptidase_S24 domain-containing protein.	Ku domain-containing protein.	0.689
HCAG_02527	HCAG_05461	A6QYS0	A6R753	Peptidase_S24 domain-containing protein.	HRDC domain-containing protein.	0.484
HCAG_02527	HCAG_08094	A6QYS0	A6REM9	Peptidase_S24 domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.484