node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msp_0071 | Msp_0263 | Msp_0071 | Msp_0263 | Predicted ribokinase; Cd01942, pfam00294, COG0524. | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | 0.920 |
Msp_0071 | pdx1 | Msp_0071 | Msp_0072 | Predicted ribokinase; Cd01942, pfam00294, COG0524. | Pyridoxine biosynthesis protein Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.916 |
Msp_0071 | pdxT | Msp_0071 | Msp_0671 | Predicted ribokinase; Cd01942, pfam00294, COG0524. | Predicted glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.825 |
Msp_0071 | prs | Msp_0071 | Msp_1229 | Predicted ribokinase; Cd01942, pfam00294, COG0524. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.942 |
Msp_0071 | rpiA | Msp_0071 | Msp_0995 | Predicted ribokinase; Cd01942, pfam00294, COG0524. | RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.921 |
Msp_0073 | pdx1 | Msp_0073 | Msp_0072 | Predicted exopolysaccharide synthesis protein; Pfam06055. | Pyridoxine biosynthesis protein Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.538 |
Msp_0263 | Msp_0071 | Msp_0263 | Msp_0071 | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | Predicted ribokinase; Cd01942, pfam00294, COG0524. | 0.920 |
Msp_0263 | pdx1 | Msp_0263 | Msp_0072 | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | Pyridoxine biosynthesis protein Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.800 |
Msp_0263 | pdxT | Msp_0263 | Msp_0671 | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | Predicted glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
Msp_0263 | prs | Msp_0263 | Msp_1229 | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.949 |
Msp_0263 | rpiA | Msp_0263 | Msp_0995 | Predicted phosphomannomutase; COG1109, pfam02878; Belongs to the phosphohexose mutase family. | RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.922 |
Msp_0489 | gatA | Msp_0489 | Msp_0181 | Conserved hypothetical protein. | GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.999 |
Msp_0489 | gatD | Msp_0489 | Msp_1411 | Conserved hypothetical protein. | GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. | 0.913 |
Msp_0489 | pdx1 | Msp_0489 | Msp_0072 | Conserved hypothetical protein. | Pyridoxine biosynthesis protein Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.538 |
Msp_0489 | pdxT | Msp_0489 | Msp_0671 | Conserved hypothetical protein. | Predicted glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.502 |
gatA | Msp_0489 | Msp_0181 | Msp_0489 | GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | Conserved hypothetical protein. | 0.999 |
gatA | gatD | Msp_0181 | Msp_1411 | GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. | 0.972 |
gatA | pdx1 | Msp_0181 | Msp_0072 | GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | Pyridoxine biosynthesis protein Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.551 |
gatA | pdxT | Msp_0181 | Msp_0671 | GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | Predicted glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.501 |
gatD | Msp_0489 | Msp_1411 | Msp_0489 | GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. | Conserved hypothetical protein. | 0.913 |