node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msp_0254 | Msp_1098 | Msp_0254 | Msp_1098 | Anaerobic ribonucleotide-triphosphate reductase. | Predicted adenylate cyclase; COG1437. | 0.900 |
Msp_0254 | mptA | Msp_0254 | Msp_0294 | Anaerobic ribonucleotide-triphosphate reductase. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.833 |
Msp_0254 | ndk | Msp_0254 | Msp_0630 | Anaerobic ribonucleotide-triphosphate reductase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.919 |
Msp_0295 | cofG | Msp_0295 | Msp_0296 | Conserved hypothetical protein; COG4077. | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.850 |
Msp_0295 | mptA | Msp_0295 | Msp_0294 | Conserved hypothetical protein; COG4077. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.904 |
Msp_1098 | Msp_0254 | Msp_1098 | Msp_0254 | Predicted adenylate cyclase; COG1437. | Anaerobic ribonucleotide-triphosphate reductase. | 0.900 |
Msp_1098 | mptA | Msp_1098 | Msp_0294 | Predicted adenylate cyclase; COG1437. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.826 |
Msp_1098 | ndk | Msp_1098 | Msp_0630 | Predicted adenylate cyclase; COG1437. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.904 |
Msp_1325 | Msp_1432 | Msp_1325 | Msp_1432 | Predicted carbonic anhydrase/acetyltransferase; COG0663. | Putative 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | 0.403 |
Msp_1325 | mptA | Msp_1325 | Msp_0294 | Predicted carbonic anhydrase/acetyltransferase; COG0663. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.625 |
Msp_1432 | Msp_1325 | Msp_1432 | Msp_1325 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | Predicted carbonic anhydrase/acetyltransferase; COG0663. | 0.403 |
Msp_1432 | mptA | Msp_1432 | Msp_0294 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.771 |
cofG | Msp_0295 | Msp_0296 | Msp_0295 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Conserved hypothetical protein; COG4077. | 0.850 |
cofG | mptA | Msp_0296 | Msp_0294 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.869 |
mfnA | mptA | Msp_0329 | Msp_0294 | MfnA; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.643 |
mptA | Msp_0254 | Msp_0294 | Msp_0254 | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Anaerobic ribonucleotide-triphosphate reductase. | 0.833 |
mptA | Msp_0295 | Msp_0294 | Msp_0295 | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Conserved hypothetical protein; COG4077. | 0.904 |
mptA | Msp_1098 | Msp_0294 | Msp_1098 | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Predicted adenylate cyclase; COG1437. | 0.826 |
mptA | Msp_1325 | Msp_0294 | Msp_1325 | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Predicted carbonic anhydrase/acetyltransferase; COG0663. | 0.625 |
mptA | Msp_1432 | Msp_0294 | Msp_1432 | Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Putative 6-pyruvoyl tetrahydrobiopterin synthase; COG0720. | 0.771 |