node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msp_0330 | cofG | Msp_0330 | Msp_0296 | Hypothetical protein. | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.676 |
Msp_0330 | cofH | Msp_0330 | Msp_0392 | Hypothetical protein. | CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.676 |
Msp_0330 | thiC1 | Msp_0330 | Msp_0228 | Hypothetical protein. | ThiC1; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.763 |
Msp_0330 | thiC2 | Msp_0330 | Msp_0251 | Hypothetical protein. | ThiC2; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.763 |
Msp_0330 | thiD | Msp_0330 | Msp_1007 | Hypothetical protein. | ThiD; Putative phosphomethylpyrimidine kinase; COG0351, cd01169. | 0.923 |
Msp_0330 | thiE | Msp_0330 | Msp_0683 | Hypothetical protein. | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.949 |
Msp_0330 | thiM1 | Msp_0330 | Msp_0682 | Hypothetical protein. | ThiM1; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.480 |
Msp_0330 | thiM2 | Msp_0330 | Msp_0694 | Hypothetical protein. | ThiM2; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.480 |
Msp_0693 | Msp_0695 | Msp_0693 | Msp_0695 | Conserved hypothetical protein; Pfam01910. | Hypothetical membrane-spanning protein. | 0.478 |
Msp_0693 | thiE | Msp_0693 | Msp_0683 | Conserved hypothetical protein; Pfam01910. | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.457 |
Msp_0693 | thiM2 | Msp_0693 | Msp_0694 | Conserved hypothetical protein; Pfam01910. | ThiM2; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.796 |
Msp_0695 | Msp_0693 | Msp_0695 | Msp_0693 | Hypothetical membrane-spanning protein. | Conserved hypothetical protein; Pfam01910. | 0.478 |
Msp_0695 | thiM2 | Msp_0695 | Msp_0694 | Hypothetical membrane-spanning protein. | ThiM2; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.478 |
cofG | Msp_0330 | Msp_0296 | Msp_0330 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Hypothetical protein. | 0.676 |
cofG | cofH | Msp_0296 | Msp_0392 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.996 |
cofG | thiC1 | Msp_0296 | Msp_0228 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | ThiC1; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.698 |
cofG | thiC2 | Msp_0296 | Msp_0251 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | ThiC2; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.698 |
cofG | thiD | Msp_0296 | Msp_1007 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | ThiD; Putative phosphomethylpyrimidine kinase; COG0351, cd01169. | 0.515 |
cofG | thiE | Msp_0296 | Msp_0683 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.889 |
cofG | thiM1 | Msp_0296 | Msp_0682 | CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | ThiM1; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.496 |