node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msp_0435 | Msp_0622 | Msp_0435 | Msp_0622 | Nicotinamide-nucleotide adenylyltransferase. | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.586 |
Msp_0435 | Msp_1167 | Msp_0435 | Msp_1167 | Nicotinamide-nucleotide adenylyltransferase. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.629 |
Msp_0435 | tiaS | Msp_0435 | Msp_1142 | Nicotinamide-nucleotide adenylyltransferase. | Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.614 |
Msp_0622 | Msp_0435 | Msp_0622 | Msp_0435 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Nicotinamide-nucleotide adenylyltransferase. | 0.586 |
Msp_0622 | Msp_1167 | Msp_0622 | Msp_1167 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.592 |
Msp_0622 | nac | Msp_0622 | Msp_0543 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.409 |
Msp_0622 | pfdB | Msp_0622 | Msp_1256 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Partially conserved hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.618 |
Msp_0622 | tiaS | Msp_0622 | Msp_1142 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.685 |
Msp_1167 | Msp_0435 | Msp_1167 | Msp_0435 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Nicotinamide-nucleotide adenylyltransferase. | 0.629 |
Msp_1167 | Msp_0622 | Msp_1167 | Msp_0622 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.592 |
Msp_1167 | Msp_1169 | Msp_1167 | Msp_1169 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Hypothetical protein. | 0.864 |
Msp_1167 | Msp_1273 | Msp_1167 | Msp_1273 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Related to metal-dependent phosphohydrolase. | 0.946 |
Msp_1167 | cobS | Msp_1167 | Msp_1168 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.892 |
Msp_1167 | dnaG | Msp_1167 | Msp_1356 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Predicted DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.617 |
Msp_1167 | nac | Msp_1167 | Msp_0543 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.677 |
Msp_1167 | pfdB | Msp_1167 | Msp_1256 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Partially conserved hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.647 |
Msp_1167 | tgtA | Msp_1167 | Msp_0520 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Predicted queuine/archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.649 |
Msp_1167 | tiaS | Msp_1167 | Msp_1142 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.597 |
Msp_1169 | Msp_1167 | Msp_1169 | Msp_1167 | Hypothetical protein. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.864 |
Msp_1169 | cobS | Msp_1169 | Msp_1168 | Hypothetical protein. | CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.892 |