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purU protein (Xanthomonas campestris campestris) - STRING interaction network
"purU" - Formyltetrahydrofolate deformylase in Xanthomonas campestris campestris
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (283 aa)    
Predicted Functional Partners:
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (294 aa)
   
 
  0.962
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (403 aa)
       
  0.929
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (217 aa)
 
 
0.926
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.926
purT
Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family (400 aa)
       
  0.924
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Methionine synthase I cobalamin-binding domain (918 aa)
       
  0.906
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (164 aa)
       
  0.902
metH1
Methionine synthase I (cobalamin-dependent) methyltransferase domain (379 aa)
       
    0.902
fdhA
Formate dehydrogenase related protein; Anaerobic dehydrogenases, typically selenocysteine-containing (990 aa)
         
    0.900
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (328 aa)
 
   
    0.837
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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