STRINGSTRING
mrdA protein (Xanthomonas campestris campestris) - STRING interaction network
"mrdA" - Peptidoglycan D,D-transpeptidase MrdA in Xanthomonas campestris campestris
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrdAPeptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily (686 aa)    
Predicted Functional Partners:
ftsW1
Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily (372 aa)
 
  0.998
mreC
Cell shape-determining protein (451 aa)
 
 
  0.992
mreB
Rod shape-determining protein; Actin-like ATPase involved in cell morphogenesis (348 aa)
 
  0.971
mreD
Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (161 aa)
 
   
  0.927
dacC
Penicillin-binding protein 6; D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family (403 aa)
 
 
  0.920
ftsI
Peptidoglycan D,D-transpeptidase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (623 aa)
 
0.893
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family (156 aa)
 
   
  0.867
ponB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (814 aa)
 
 
  0.845
ftsW2
Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily (454 aa)
 
  0.793
mrcA
Membrane carboxypeptidase/penicillin-binding protein (811 aa)
   
 
  0.767
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
Server load: low (14%) [HD]