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XCC3253 protein (Xanthomonas campestris campestris) - STRING interaction network
"XCC3253" - dITP/XTP pyrophosphatase in Xanthomonas campestris campestris
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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XCC3253dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family (199 aa)    
Predicted Functional Partners:
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (485 aa)
   
  0.994
rph
Ribonuclease PH; Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (241 aa)
 
        0.989
guaA1
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (521 aa)
 
 
  0.967
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (141 aa)
   
  0.925
XCC3252
Uncharacterized protein; Lactoylglutathione lyase and related lyases (130 aa)
     
      0.908
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (259 aa)
   
 
  0.907
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Unnamed protein product (184 aa)
   
 
    0.905
guaA2
GMP synthase - Glutamine amidotransferase domain (254 aa)
   
 
  0.904
XCC1547
annotation not available (321 aa)
         
  0.902
hemN
Oxygen-independent coproporphyrinogen-III oxidase-like protein; Involved in the biosynthesis of porphyrin-containing compound (385 aa)
   
   
  0.882
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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