STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (186 aa)    
Predicted Functional Partners:
guaA1
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP
  
 0.993
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
  
 0.974
purH
Bifunctional purine biosynthesis protein PurH; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
 
 
 0.954
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP
  
 
 0.951
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family
  
 
 0.943
guaA2
GMP synthase - Glutamine amidotransferase domain
  
 
 0.927
XCC3471
Sugar kinases ribokinase family
   
 0.919
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family
  
 
  0.911
XCC2881
Uncharacterized protein; Predicted pyrophosphatase
  
 
  0.910
rlhA
Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family
    
 0.909
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
Server load: low (9%) [HD]