STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eddDihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family (638 aa)    
Predicted Functional Partners:
eda
KDPG and KHG aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase
 
 0.999
pgl
6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase
 
 0.994
idnK
Gluconokinase; Gluconate kinase
  
 
 0.983
gnd
6-phosphogluconate dehydrogenase
     
 0.961
kdgK
Sugar kinases, ribokinase family
  
 
 0.912
zwf1
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
 
  
 0.895
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family
 
 
 0.885
gltB
Glutamate synthase, alpha subunit; Glutamate synthase domain 2
  
  
 0.832
glk1
Glucokinase; Belongs to the bacterial glucokinase family
 
  
 0.823
zwf2
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
 
  
 0.779
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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