Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Fe2+ transport system protein A (96 aa)
Predicted Functional Partners:
Fe2+ transport system protein B (619 aa)
annotation not available (82 aa)
Succinate dehydrogenase/fumarate reductase cytochrome b subunit (131 aa)
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins (199 aa)
annotation not available (164 aa)
Enoyl-CoA hydratase/carnithine racemase (265 aa)
annotation not available (839 aa)
annotation not available (98 aa)
Valine-pyruvate aminotransferase; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs (456 aa)
Uncharacterized protein conserved in bacteria (242 aa)