STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (467 aa)
Predicted Functional Partners:
Succinate dehydrogenase/fumarate reductase cytochrome b subunit (131 aa)
Succinate dehydrogenase/fumarate reductase flavoprotein subunits; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily (596 aa)
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (328 aa)
Malic enzyme (775 aa)
Succinate dehydrogenase/fumarate reductase Fe-S protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family (260 aa)
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (583 aa)
Citrate synthase; Belongs to the citrate synthase family (452 aa)
Malate synthase (540 aa)
2-oxoglutarate dehydrogenase complex,dehydrogenase (E1) component, and related enzymes (990 aa)