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hpt protein (Xanthomonas campestris campestris) - STRING interaction network
"hpt" - Hypoxanthine-guanine phosphoribosyltransferase in Xanthomonas campestris campestris
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hptHypoxanthine-guanine phosphoribosyltransferase; Unnamed protein product (184 aa)    
Predicted Functional Partners:
guaA1
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (521 aa)
   
 
  0.976
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (430 aa)
   
 
  0.965
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (485 aa)
   
 
  0.963
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (203 aa)
         
  0.940
purH
Bifunctional purine biosynthesis protein PurH; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) (527 aa)
   
 
  0.935
guaA2
GMP synthase - Glutamine amidotransferase domain (254 aa)
       
  0.920
XCC2881
Uncharacterized protein; Predicted pyrophosphatase (274 aa)
       
    0.911
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (186 aa)
   
  0.907
XCC3253
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family (199 aa)
   
 
    0.905
rlhA
Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family (312 aa)
     
 
  0.904
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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