STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (430 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
 
 
 0.994
purH
Bifunctional purine biosynthesis protein PurH; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
 
 0.987
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family
 
 
 0.986
pyrB
Aspartate carbamoyltransferase catalytic chain; Belongs to the ATCase/OTCase family
 
 
 0.976
XCC2741
Bifunctional diaminopimelate decarboxylase/aspartate kinase; Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family
  
 
 0.969
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Unnamed protein product
  
 
 0.965
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily
  
 
 0.949
asnB2
Asparagine synthase (glutamine-hydrolyzing)
  
 
 0.910
asnB1
Asparagine synthase (glutamine-hydrolyzing)
  
 
 0.910
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family
  
 
  0.909
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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