STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (432 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde aminotransferase
 
 0.998
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family
  
 0.995
XCC2003
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
 
 0.966
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family
 
  
 0.961
gltX
Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily
   
 
 0.956
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
  
  
 0.945
cysG
Siroheme synthase; Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family
 
 
 0.899
XCC0866
Uncharacterized protein; Predicted O-linked N-acetylglucosamine transferase SPINDLY family
       0.898
hemD
Uroporphyrinogen-III synthase
  
 
 0.897
XCC2010
Uroporphyrin-III C-methyltransferase; Uroporphyrinogen-III methylase
 
 
 0.891
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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