Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases (449 aa)
Predicted Functional Partners:
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family (239 aa)
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (295 aa)
VisC protein; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases (393 aa)
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate (301 aa)
Uncharacterized protein (185 aa)
annotation not available (192 aa)
Acetoin utilization family protein; Deacetylases including yeast histone deacetylase and acetoin utilization protein (302 aa)
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family (332 aa)
Xaa-Pro aminopeptidase (443 aa)
Hydrolase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) (238 aa)