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metF1 protein (Xanthomonas campestris campestris) - STRING interaction network
"metF1" - 510-methylenetetrahydrofolate reductase in Xanthomonas campestris campestris
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
metF1510-methylenetetrahydrofolate reductase (285 aa)    
Predicted Functional Partners:
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Methionine synthase I cobalamin-binding domain (918 aa)
 
  0.991
metH1
Methionine synthase I (cobalamin-dependent) methyltransferase domain (379 aa)
  0.980
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.973
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (294 aa)
   
 
  0.952
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Methionine synthase II (cobalamin-independent) (343 aa)
 
 
  0.946
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (403 aa)
   
 
  0.930
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis (264 aa)
   
 
  0.920
thrA
Bifunctional aspartokinase/homoserine dehydrogenase I; Aspartokinases (835 aa)
   
 
  0.904
XCC2856
Cystathionine beta-lyases/cystathionine gamma-synthases (405 aa)
   
 
  0.898
metR
Transcriptional regulator (301 aa)
   
   
  0.893
Your Current Organism:
Xanthomonas campestris campestris
NCBI taxonomy Id: 340
Other names: X. campestris pv. campestris, Xanthomonas campestris, Xanthomonas campestris (pv. campestris), Xanthomonas campestris campestris, Xanthomonas campestris pv. campestris
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