STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Predicted membrane protein/domain (381 aa)
Predicted Functional Partners:
Tfp pilus assembly protein major pilin PilA (246 aa)
Protein Smg homolog; Uncharacterized protein conserved in bacteria; Belongs to the Smg family (157 aa)
annotation not available (332 aa)
Outer membrane receptor proteins mostly Fe transport (961 aa)
annotation not available (152 aa)
annotation not available (214 aa)
DNA processing chain A; Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake (378 aa)
annotation not available (270 aa)
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (831 aa)