Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Periplasmic protein TonB, links inner and outer membranes (335 aa)
Predicted Functional Partners:
annotation not available (198 aa)
Outer membrane receptor proteins mostly Fe transport (959 aa)
annotation not available (159 aa)
Outer membrane protein and related peptidoglycan-associated (lipo)proteins; Belongs to the ompA family (365 aa)
Uncharacterized protein; FOG- TPR repeat (398 aa)
annotation not available (300 aa)
Biopolymer transport protein ExbB; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity) (253 aa)
annotation not available (60 aa)
annotation not available (196 aa)
Outer membrane receptor proteins, mostly Fe transport (1003 aa)