STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
GTP cyclohydrolase 1; Unnamed protein product (209 aa)
Predicted Functional Partners:
GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5’-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family (377 aa)
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (376 aa)
6-pyruvoyl-tetrahydropterin synthase (117 aa)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 78-dihydro-6-hydroxymethylpterin- pyrophosphokina se (161 aa)
Alkaline phosphatase; Unnamed protein product; Belongs to the alkaline phosphatase family (606 aa)
GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate (339 aa)
Uncharacterized protein; Phosphodiesterase/alkaline phosphatase D (530 aa)