STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck. (491 aa)    
Predicted Functional Partners:
G3AQ39_SPAPN
Cytoplasmic dynein heavy chain.
   
 0.998
G3AIZ5_SPAPN
Uncharacterized protein.
    
 
 0.920
G3AKX9_SPAPN
Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.
     
  0.900
G3AQY3_SPAPN
PNPLA domain-containing protein.
     
  0.900
G3AIC0_SPAPN
Uncharacterized protein.
   
 0.889
G3ASJ1_SPAPN
Uncharacterized protein.
    
 0.877
G3AMS5_SPAPN
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.832
G3ALL2_SPAPN
Uncharacterized protein.
    
 0.795
G3ATS9_SPAPN
WD_REPEATS_REGION domain-containing protein.
  
 
 0.734
G3AF17_SPAPN
Uncharacterized protein.
    
 0.726
Your Current Organism:
Spathaspora passalidarum
NCBI taxonomy Id: 619300
Other names: S. passalidarum NRRL Y-27907, Spathaspora passalidarum NRRL Y-27907
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.