node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cag_0076 | Cag_0079 | Cag_0076 | Cag_0079 | Cell wall hydrolase/autolysin. | 8-amino-7-oxononanoate synthase. | 0.487 |
Cag_0076 | Cag_0080 | Cag_0076 | Cag_0080 | Cell wall hydrolase/autolysin. | Conserved hypothetical protein. | 0.487 |
Cag_0076 | bioA | Cag_0076 | Cag_0083 | Cell wall hydrolase/autolysin. | Aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.468 |
Cag_0076 | bioB | Cag_0076 | Cag_0078 | Cell wall hydrolase/autolysin. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.499 |
Cag_0076 | bioC | Cag_0076 | Cag_0081 | Cell wall hydrolase/autolysin. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.506 |
Cag_0076 | bioD | Cag_0076 | Cag_0082 | Cell wall hydrolase/autolysin. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.486 |
Cag_0076 | birA | Cag_0076 | Cag_0077 | Cell wall hydrolase/autolysin. | Biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.591 |
Cag_0076 | topA | Cag_0076 | Cag_0075 | Cell wall hydrolase/autolysin. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.577 |
Cag_0079 | Cag_0076 | Cag_0079 | Cag_0076 | 8-amino-7-oxononanoate synthase. | Cell wall hydrolase/autolysin. | 0.487 |
Cag_0079 | Cag_0080 | Cag_0079 | Cag_0080 | 8-amino-7-oxononanoate synthase. | Conserved hypothetical protein. | 0.985 |
Cag_0079 | Cag_0226 | Cag_0079 | Cag_0226 | 8-amino-7-oxononanoate synthase. | 8-amino-7-oxononanoate synthase. | 0.921 |
Cag_0079 | bioA | Cag_0079 | Cag_0083 | 8-amino-7-oxononanoate synthase. | Aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.991 |
Cag_0079 | bioB | Cag_0079 | Cag_0078 | 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.960 |
Cag_0079 | bioC | Cag_0079 | Cag_0081 | 8-amino-7-oxononanoate synthase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.914 |
Cag_0079 | bioD | Cag_0079 | Cag_0082 | 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.976 |
Cag_0079 | birA | Cag_0079 | Cag_0077 | 8-amino-7-oxononanoate synthase. | Biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.844 |
Cag_0079 | topA | Cag_0079 | Cag_0075 | 8-amino-7-oxononanoate synthase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.480 |
Cag_0080 | Cag_0076 | Cag_0080 | Cag_0076 | Conserved hypothetical protein. | Cell wall hydrolase/autolysin. | 0.487 |
Cag_0080 | Cag_0079 | Cag_0080 | Cag_0079 | Conserved hypothetical protein. | 8-amino-7-oxononanoate synthase. | 0.985 |
Cag_0080 | Cag_0226 | Cag_0080 | Cag_0226 | Conserved hypothetical protein. | 8-amino-7-oxononanoate synthase. | 0.906 |