STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I. (223 aa)    
Predicted Functional Partners:
Cag_0230
7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
  
 0.995
Cag_0373
6-pyruvoyltetrahydropterin synthase.
  
 
 0.990
Cag_0420
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 0.960
Cag_0421
6-pyruvoyl tetrahydrobiopterin synthase, putative.
  
 
 0.958
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.946
Cag_0233
Dihydroneopterin aldolase family; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.945
Cag_0787
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
   
 
  0.901
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.838
Cag_1775
Metal dependent phosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
Cag_0374
Conserved hypothetical protein.
       0.773
Your Current Organism:
Chlorobium chlorochromatii
NCBI taxonomy Id: 340177
Other names: C. chlorochromatii CaD3, Chlorobium chlorochromatii CaD3, Chlorobium chlorochromatii str. CaD3, Chlorobium chlorochromatii strain CaD3
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