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polC protein (Staphylococcus saprophyticus) - STRING interaction network
"polC" - DNA polymerase III PolC-type in Staphylococcus saprophyticus
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
polCDNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (1438 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (876 aa)
     
  0.984
SSP0002
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (376 aa)
 
 
  0.941
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (570 aa)
       
  0.933
SSP1171
Uncharacterized protein; Similar to gi|57286165|gb|AAW38259.1| [Staphylococcus aureus subsp. aureus COL], percent identity 79 in 324 aa, BLASTP E()- e-147 (324 aa)
 
   
  0.923
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (149 aa)
       
    0.904
pyk
Pyruvate kinase; Similar to gi|27468291|ref|NP_764928.1| [Staphylococcus epidermidis ATCC 12228], percent identity 87 in 586 aa, BLASTP E()- 0.0; Belongs to the pyruvate kinase family (586 aa)
         
  0.904
SSP0144
Anaerobic ribonucleoside-triphosphate reductase; Similar to gi|15925607|ref|NP_373141.1| [Staphylococcus aureus subsp. aureus Mu50], percent identity 79 in 612 aa, BLASTP E()- 0.0 (616 aa)
       
    0.901
SSP2272
DNA polymerase III delta&apos subunit; Similar to gi|27469217|ref|NP_765854.1| [Staphylococcus epidermidis ATCC 12228], percent identity 76 in 307 aa, BLASTP E()- e-137 (309 aa)
       
  0.896
SSP1064
DNA-directed DNA polymerase; Similar to gi|27468296|ref|NP_764933.1| [Staphylococcus epidermidis ATCC 12228], percent identity 68 in 1068 aa, BLASTP E()- 0.0 (1067 aa)
   
 
0.865
SSP0897
Putative exonuclease; Similar to gi|15924884|ref|NP_372418.1| [Staphylococcus aureus subsp. aureus Mu50], percent identity 74 in 183 aa, BLASTP E()- 3e-79 (184 aa)
         
0.808
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 342451
Other names: S. saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus, Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus ATCC15305, Staphylococcus saprophyticus subsp. saprophyticus CIP 76.125, Staphylococcus saprophyticus subsp. saprophyticus DSM 20229, Staphylococcus saprophyticus subsp. saprophyticus NCTC 7292, Staphylococcus saprophyticus subsp. saprophyticus str. ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus strain ATCC 15305
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