STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
cdsAPhosphatidate cytidylyltransferase; Similar to gi|27467855|ref|NP_764492.1| [Staphylococcus epidermidis ATCC 12228], percent identity 86 in 259 aa, BLASTP E(): e-128 (260 aa)    
Predicted Functional Partners:
Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Phosphatidylglycerophosphate synthase; Similar to gi|57286039|gb|AAW38133.1| [Staphylococcus aureus subsp. aureus COL], percent identity 85 in 192 aa, BLASTP E(): 1e-87; Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway (By similarity); Belongs to the diacylglycerol/lipid kinase family
1-acyl-sn-glycerol-3-phosphate acyltransferase; Similar to gi|27468322|ref|NP_764959.1| [Staphylococcus epidermidis ATCC 12228], percent identity 72 in 201 aa, BLASTP E(): 4e-82; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
Zinc metalloprotease; Similar to gi|27467856|ref|NP_764493.1| [Staphylococcus epidermidis ATCC 12228], percent identity 77 in 428 aa, BLASTP E(): 0.0
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
30S ribosomal protein S2; Similar to gi|27467850|ref|NP_764487.1| [Staphylococcus epidermidis ATCC 12228], percent identity 95 in 262 aa, BLASTP E(): e-139; Belongs to the universal ribosomal protein uS2 family
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 342451
Other names: S. saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus, Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus ATCC15305, Staphylococcus saprophyticus subsp. saprophyticus CIP 76.125, Staphylococcus saprophyticus subsp. saprophyticus DSM 20229, Staphylococcus saprophyticus subsp. saprophyticus NCTC 7292, Staphylococcus saprophyticus subsp. saprophyticus str. ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus strain ATCC 15305
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