STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (340 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.998
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.906
Patl_3578
KEGG: vvy:VV0652 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
     
 0.900
glpE
Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
     
 0.882
Patl_0064
PFAM: Rhomboid-like protein; KEGG: cps:CPS_0123 putative GlpG protein.
       0.881
Patl_2556
8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II aminotransferase class-III; KEGG: pfo:Pfl_5175 8-amino-7-oxononanoate synthase.
 
  
 0.638
Patl_0058
KEGG: noc:Noc_1149 hypothetical protein.
       0.478
Patl_0059
KEGG: cps:CPS_0951 hypothetical protein.
       0.478
Patl_0060
TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL; KEGG: cps:CPS_0952 GGDEF/EAL domain protein.
       0.478
Your Current Organism:
Pseudoalteromonas atlantica
NCBI taxonomy Id: 342610
Other names: P. atlantica T6c, Pseudoalteromonas atlantica T6c, Pseudoalteromonas atlantica str. T6c, Pseudoalteromonas atlantica strain T6c
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