node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NP_2022A | citG | NP_2022A | NP_2024A | DUF447 family protein. | triphosphoribosyl-dephospho-CoA synthase. | 0.950 |
NP_2022A | cofC | NP_2022A | NP_2400A | DUF447 family protein. | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.409 |
NP_2022A | cofD | NP_2022A | NP_2028A | DUF447 family protein. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.857 |
NP_2022A | dpd | NP_2022A | NP_2026A | DUF447 family protein. | Putative dihydropyrimidine dehydrogenase. | 0.922 |
NP_4374A | cofD | NP_4374A | NP_2028A | Probable F420-dependent oxidoreductase. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.778 |
NP_4374A | cofE | NP_4374A | NP_1054A | Probable F420-dependent oxidoreductase. | Coenzyme F420:L-glutamate ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.775 |
NP_4374A | cofG | NP_4374A | NP_2398A | Probable F420-dependent oxidoreductase. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.732 |
NP_4374A | cofH | NP_4374A | NP_2394A | Probable F420-dependent oxidoreductase. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2. | 0.487 |
NP_4374A | npdG | NP_4374A | NP_0756A | Probable F420-dependent oxidoreductase. | F420H2:NADP oxidoreductase. | 0.643 |
citG | NP_2022A | NP_2024A | NP_2022A | triphosphoribosyl-dephospho-CoA synthase. | DUF447 family protein. | 0.950 |
citG | cofC | NP_2024A | NP_2400A | triphosphoribosyl-dephospho-CoA synthase. | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.556 |
citG | cofD | NP_2024A | NP_2028A | triphosphoribosyl-dephospho-CoA synthase. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.880 |
citG | dpd | NP_2024A | NP_2026A | triphosphoribosyl-dephospho-CoA synthase. | Putative dihydropyrimidine dehydrogenase. | 0.914 |
citG | mer | NP_2024A | NP_1056A | triphosphoribosyl-dephospho-CoA synthase. | Probable 5,10-methylenetetrahydrofolate reductase; Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT. | 0.470 |
cofC | NP_2022A | NP_2400A | NP_2022A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | DUF447 family protein. | 0.409 |
cofC | citG | NP_2400A | NP_2024A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | triphosphoribosyl-dephospho-CoA synthase. | 0.556 |
cofC | cofD | NP_2400A | NP_2028A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.977 |
cofC | cofE | NP_2400A | NP_1054A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Coenzyme F420:L-glutamate ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.786 |
cofC | cofG | NP_2400A | NP_2398A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.872 |
cofC | cofH | NP_2400A | NP_2394A | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2. | 0.718 |