STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ubiA2(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (277 aa)    
Predicted Functional Partners:
pcrB
(S)-3-O-geranylgeranylglyceryl phosphate synthase 1; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
    
 0.970
carS
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
 
  
 0.962
NP_4564A
FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase).
 
 
 0.958
NP_4472A
YneT family protein.
       0.766
idiA
Isopentenyl-diphosphate delta-isomerase, type I.
 
 
 0.707
idsA3
Bifunctional short chain isoprenyl diphosphate synthase; Probably involved in biosynthesis of the precursor for C25 (sesterterpanyl chain) moiety of C20-C25 diether (2-O-sesterterpanyl-3- O-phytanyl-sn-glycer) membrane lipid. Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylfarnesyl diphosphate (GFPP). Geranylgeranyl diphosphate (GGPP) is the preferred substrate, but dimethylallyl diphosphate (DMAPP) and farnesyl diphosphate (FPP) can also be used as allylic substrate.
 
 
 0.706
idsA2
Bifunctional short chain isoprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.621
lyeJ
Lycopene elongase / lycopene 1,2-hydratase.
  
  
 0.593
ubiA3
UbiA family prenyltransferase.
  
  
  0.589
idiB
Isopentenyl-diphosphate delta-isomerase, type II; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.580
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
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