node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP69032.1 | ABP70856.1 | Rsph17025_0121 | Rsph17025_1965 | PFAM: aminotransferase, class I and II. | PFAM: asparagine synthase. | 0.924 |
ABP69032.1 | argG | Rsph17025_0121 | Rsph17025_2650 | PFAM: aminotransferase, class I and II. | PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.930 |
ABP69032.1 | purA | Rsph17025_0121 | Rsph17025_0875 | PFAM: aminotransferase, class I and II. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.930 |
ABP69032.1 | pyrB | Rsph17025_0121 | Rsph17025_0223 | PFAM: aminotransferase, class I and II. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.900 |
ABP69945.1 | ABP71162.1 | Rsph17025_1044 | Rsph17025_2272 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.491 |
ABP69945.1 | guaA | Rsph17025_1044 | Rsph17025_1867 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.966 |
ABP69945.1 | guaB | Rsph17025_1044 | Rsph17025_1152 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.956 |
ABP69945.1 | purA | Rsph17025_1044 | Rsph17025_0875 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.952 |
ABP69945.1 | purD | Rsph17025_1044 | Rsph17025_0635 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.481 |
ABP69945.1 | purH | Rsph17025_1044 | Rsph17025_2928 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.946 |
ABP70856.1 | ABP69032.1 | Rsph17025_1965 | Rsph17025_0121 | PFAM: asparagine synthase. | PFAM: aminotransferase, class I and II. | 0.924 |
ABP70856.1 | argG | Rsph17025_1965 | Rsph17025_2650 | PFAM: asparagine synthase. | PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.929 |
ABP70856.1 | guaA | Rsph17025_1965 | Rsph17025_1867 | PFAM: asparagine synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.606 |
ABP70856.1 | guaB | Rsph17025_1965 | Rsph17025_1152 | PFAM: asparagine synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.419 |
ABP70856.1 | purA | Rsph17025_1965 | Rsph17025_0875 | PFAM: asparagine synthase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.938 |
ABP70856.1 | pyrB | Rsph17025_1965 | Rsph17025_0223 | PFAM: asparagine synthase. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.936 |
ABP71162.1 | ABP69945.1 | Rsph17025_2272 | Rsph17025_1044 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.491 |
ABP71162.1 | guaA | Rsph17025_2272 | Rsph17025_1867 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.955 |
ABP71162.1 | guaB | Rsph17025_2272 | Rsph17025_1152 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.946 |
ABP71162.1 | purA | Rsph17025_2272 | Rsph17025_0875 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.998 |