node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP70065.1 | ABP70068.1 | Rsph17025_1164 | Rsph17025_1167 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | PFAM: Usg family protein. | 0.521 |
ABP70065.1 | argS | Rsph17025_1164 | Rsph17025_0902 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: arginyl-tRNA synthetase. | 0.915 |
ABP70065.1 | gyrA | Rsph17025_1164 | Rsph17025_1166 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.871 |
ABP70065.1 | proS | Rsph17025_1164 | Rsph17025_0401 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.907 |
ABP70065.1 | pyrG | Rsph17025_1164 | Rsph17025_0873 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.735 |
ABP70065.1 | trmFO | Rsph17025_1164 | Rsph17025_1165 | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.850 |
ABP70068.1 | ABP70065.1 | Rsph17025_1167 | Rsph17025_1164 | PFAM: Usg family protein. | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.521 |
ABP70068.1 | gyrA | Rsph17025_1167 | Rsph17025_1166 | PFAM: Usg family protein. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.637 |
ABP70068.1 | trmFO | Rsph17025_1167 | Rsph17025_1165 | PFAM: Usg family protein. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.527 |
ABP70337.1 | trmFO | Rsph17025_1443 | Rsph17025_1165 | PFAM: Allergen V5/Tpx-1 family protein. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.485 |
ABP71041.1 | proS | Rsph17025_2151 | Rsph17025_0401 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.890 |
ABP71041.1 | pyrG | Rsph17025_2151 | Rsph17025_0873 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.796 |
ABP71041.1 | trmD | Rsph17025_2151 | Rsph17025_0184 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.714 |
ABP71041.1 | trmFO | Rsph17025_2151 | Rsph17025_1165 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.861 |
argS | ABP70065.1 | Rsph17025_0902 | Rsph17025_1164 | TIGRFAM: arginyl-tRNA synthetase. | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.915 |
argS | gyrA | Rsph17025_0902 | Rsph17025_1166 | TIGRFAM: arginyl-tRNA synthetase. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.469 |
argS | proS | Rsph17025_0902 | Rsph17025_0401 | TIGRFAM: arginyl-tRNA synthetase. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.984 |
argS | pyrG | Rsph17025_0902 | Rsph17025_0873 | TIGRFAM: arginyl-tRNA synthetase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.920 |
argS | trmFO | Rsph17025_0902 | Rsph17025_1165 | TIGRFAM: arginyl-tRNA synthetase. | Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.559 |
gyrA | ABP70065.1 | Rsph17025_1166 | Rsph17025_1164 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Glutamate--tRNA ligase; PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.871 |