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glmU protein (Rhodobacter sphaeroides ATCC17025) - STRING interaction network
"glmU" - Bifunctional protein GlmU in Rhodobacter sphaeroides ATCC17025
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain; In the C-terminal section; belongs to the transferase hexapeptide repeat family (454 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family (447 aa)
 
  0.997
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (603 aa)
 
  0.992
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily (422 aa)
 
  0.970
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (339 aa)
   
  0.947
ABP71033.1
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (260 aa)
   
 
  0.907
ABP71840.1
PFAM- aminoglycoside phosphotransferase (342 aa)
     
 
  0.904
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family (470 aa)
 
 
  0.728
ABP71580.1
PFAM- phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase (473 aa)
   
 
  0.674
ABP71541.1
Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM- phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding (751 aa)
   
 
  0.667
ABP69184.1
Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM- phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding (759 aa)
   
 
  0.667
Your Current Organism:
Rhodobacter sphaeroides ATCC17025
NCBI taxonomy Id: 349102
Other names: R. sphaeroides ATCC 17025, Rhodobacter sphaeroides ATCC 17025, Rhodobacter sphaeroides ATCC17025, Rhodobacter sphaeroides str. ATCC 17025, Rhodobacter sphaeroides strain ATCC 17025
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