STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcl1Citrate (pro-3S)-lyase; Involved in the ethylmalonyl-CoA pathway for acetate assimilation. Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA (By similarity). (379 aa)    
Predicted Functional Partners:
ABP68996.1
PFAM: MaoC domain protein dehydratase.
 
 
 0.978
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.929
ABP71580.1
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase.
  
 
 0.928
ABP71077.1
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
 0.927
ABP71191.1
Carbamoyl-phosphate synthase L chain, ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp.
  
 
 0.923
ABP70226.1
PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
 0.922
mcl2
Citrate (pro-3S)-lyase; Catalyzes the hydrolysis of (3S)-malyl-CoA to (3S)-malate and free CoA. Inactive towards beta-methylmalyl-CoA and other CoA esters (By similarity); Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.917
ABP71194.1
Propionyl-CoA carboxylase; PFAM: carboxyl transferase.
  
 
 0.916
ABP69119.1
PFAM: FAD linked oxidase domain protein.
  
  
  0.911
ABP70909.1
Serine--glyoxylate transaminase; PFAM: aminotransferase, class V.
  
 
 0.910
Your Current Organism:
Rhodobacter sphaeroides ATCC 17025
NCBI taxonomy Id: 349102
Other names: R. sphaeroides ATCC 17025, Rhodobacter sphaeroides str. ATCC 17025, Rhodobacter sphaeroides strain ATCC 17025
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.