node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP68976.1 | ABP69106.1 | Rsph17025_0064 | Rsph17025_0196 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | 0.507 |
ABP68976.1 | ABP71645.1 | Rsph17025_0064 | Rsph17025_2758 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | 0.402 |
ABP68976.1 | mutM | Rsph17025_0064 | Rsph17025_2592 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.631 |
ABP68976.1 | polA | Rsph17025_0064 | Rsph17025_0200 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.639 |
ABP69106.1 | ABP68976.1 | Rsph17025_0196 | Rsph17025_0064 | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.507 |
ABP69106.1 | ABP71645.1 | Rsph17025_0196 | Rsph17025_2758 | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | 0.472 |
ABP69106.1 | mutM | Rsph17025_0196 | Rsph17025_2592 | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.414 |
ABP69106.1 | polA | Rsph17025_0196 | Rsph17025_0200 | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.769 |
ABP69932.1 | ABP71645.1 | Rsph17025_1031 | Rsph17025_2758 | PFAM: Ppx/GppA phosphatase. | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | 0.493 |
ABP69932.1 | polA | Rsph17025_1031 | Rsph17025_0200 | PFAM: Ppx/GppA phosphatase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.514 |
ABP71645.1 | ABP68976.1 | Rsph17025_2758 | Rsph17025_0064 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.402 |
ABP71645.1 | ABP69106.1 | Rsph17025_2758 | Rsph17025_0196 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase. | 0.472 |
ABP71645.1 | ABP69932.1 | Rsph17025_2758 | Rsph17025_1031 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | PFAM: Ppx/GppA phosphatase. | 0.493 |
ABP71645.1 | ABP71647.1 | Rsph17025_2758 | Rsph17025_2760 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase. | 0.807 |
ABP71645.1 | ABP71649.1 | Rsph17025_2758 | Rsph17025_2762 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.464 |
ABP71645.1 | ABP71650.1 | Rsph17025_2758 | Rsph17025_2763 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | PFAM: OmpA/MotB domain protein. | 0.444 |
ABP71645.1 | argJ | Rsph17025_2758 | Rsph17025_2759 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | N-acetylglutamate synthase / glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.854 |
ABP71645.1 | mutM | Rsph17025_2758 | Rsph17025_2592 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.432 |
ABP71645.1 | polA | Rsph17025_2758 | Rsph17025_0200 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.518 |
ABP71645.1 | secA | Rsph17025_2758 | Rsph17025_2761 | PFAM: NUDIX hydrolase; Belongs to the Nudix hydrolase family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.641 |