node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABQ94488.1 | ABQ94762.1 | PsycPRwf_1547 | PsycPRwf_1822 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.893 |
ABQ94488.1 | ABQ95202.1 | PsycPRwf_1547 | PsycPRwf_2262 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.949 |
ABQ94488.1 | cysG | PsycPRwf_1547 | PsycPRwf_1107 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.985 |
ABQ94488.1 | hemA | PsycPRwf_1547 | PsycPRwf_0311 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.814 |
ABQ94488.1 | hemC | PsycPRwf_1547 | PsycPRwf_2263 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.991 |
ABQ94488.1 | hemE | PsycPRwf_1547 | PsycPRwf_1599 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.944 |
ABQ94488.1 | hemL | PsycPRwf_1547 | PsycPRwf_0330 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.790 |
ABQ94762.1 | ABQ94488.1 | PsycPRwf_1822 | PsycPRwf_1547 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.893 |
ABQ94762.1 | ABQ95202.1 | PsycPRwf_1822 | PsycPRwf_2262 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.781 |
ABQ94762.1 | cysG | PsycPRwf_1822 | PsycPRwf_1107 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.860 |
ABQ94762.1 | hemA | PsycPRwf_1822 | PsycPRwf_0311 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.842 |
ABQ94762.1 | hemC | PsycPRwf_1822 | PsycPRwf_2263 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.994 |
ABQ94762.1 | hemE | PsycPRwf_1822 | PsycPRwf_1599 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.685 |
ABQ94762.1 | hemL | PsycPRwf_1822 | PsycPRwf_0330 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.990 |
ABQ94762.1 | nadE | PsycPRwf_1822 | PsycPRwf_1882 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.429 |
ABQ95202.1 | ABQ94488.1 | PsycPRwf_2262 | PsycPRwf_1547 | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.949 |
ABQ95202.1 | ABQ94762.1 | PsycPRwf_2262 | PsycPRwf_1822 | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.781 |
ABQ95202.1 | cysG | PsycPRwf_2262 | PsycPRwf_1107 | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.949 |
ABQ95202.1 | hemA | PsycPRwf_2262 | PsycPRwf_0311 | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.444 |
ABQ95202.1 | hemC | PsycPRwf_2262 | PsycPRwf_2263 | Uroporphyrinogen-III synthase-like protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.993 |