node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hhal_0129 | Hhal_2274 | Hhal_0129 | Hhal_2274 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
Hhal_0129 | Hhal_2275 | Hhal_0129 | Hhal_2275 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | KEGG: aeh:Mlg_2770 pyridine nucleotide transhydrogenase subunit alpha. | 0.900 |
Hhal_0129 | Hhal_2276 | Hhal_0129 | Hhal_2276 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific). | 0.900 |
Hhal_0129 | cobB | Hhal_0129 | Hhal_1597 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | PFAM: Silent information regulator protein Sir2; KEGG: rxy:Rxyl_1341 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.900 |
Hhal_0129 | nadD | Hhal_0129 | Hhal_2141 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
Hhal_0129 | nadE | Hhal_0129 | Hhal_2238 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | DNA-directed RNA polymerase, subunit H; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.900 |
Hhal_0129 | nadK | Hhal_0129 | Hhal_1479 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.900 |
Hhal_0129 | surE | Hhal_0129 | Hhal_1431 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Hhal_1029 | Hhal_2275 | Hhal_1029 | Hhal_2275 | Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: aeh:Mlg_0246 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). | KEGG: aeh:Mlg_2770 pyridine nucleotide transhydrogenase subunit alpha. | 0.407 |
Hhal_1029 | Hhal_2276 | Hhal_1029 | Hhal_2276 | Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: aeh:Mlg_0246 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). | PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific). | 0.407 |
Hhal_1029 | cobB | Hhal_1029 | Hhal_1597 | Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: aeh:Mlg_0246 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). | PFAM: Silent information regulator protein Sir2; KEGG: rxy:Rxyl_1341 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.514 |
Hhal_1029 | nadK | Hhal_1029 | Hhal_1479 | Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: aeh:Mlg_0246 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.633 |
Hhal_1480 | nadK | Hhal_1480 | Hhal_1479 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.964 |
Hhal_2274 | Hhal_0129 | Hhal_2274 | Hhal_0129 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aeh:Mlg_1457 MazG family protein. | 0.900 |
Hhal_2274 | Hhal_2275 | Hhal_2274 | Hhal_2275 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | KEGG: aeh:Mlg_2770 pyridine nucleotide transhydrogenase subunit alpha. | 0.999 |
Hhal_2274 | Hhal_2276 | Hhal_2274 | Hhal_2276 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific). | 0.999 |
Hhal_2274 | cobB | Hhal_2274 | Hhal_1597 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | PFAM: Silent information regulator protein Sir2; KEGG: rxy:Rxyl_1341 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.900 |
Hhal_2274 | nadD | Hhal_2274 | Hhal_2141 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.901 |
Hhal_2274 | nadE | Hhal_2274 | Hhal_2238 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | DNA-directed RNA polymerase, subunit H; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.936 |
Hhal_2274 | nadK | Hhal_2274 | Hhal_1479 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.903 |