node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dred_0293 | dacA | Dred_0293 | Dred_0292 | PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.991 |
Dred_0293 | glmM | Dred_0293 | Dred_0294 | PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.576 |
Dred_0293 | glmS | Dred_0293 | Dred_0295 | PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.435 |
Dred_1383 | glmM | Dred_1383 | Dred_0294 | TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: chy:CHY_0976 glucose-1-phosphate thymidylyltransferase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.626 |
Dred_1810 | glmM | Dred_1810 | Dred_0294 | PFAM: hexokinase; KEGG: dre:406339 hexokinase 2. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.918 |
Dred_1810 | glmS | Dred_1810 | Dred_0295 | PFAM: hexokinase; KEGG: dre:406339 hexokinase 2. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.912 |
Dred_3054 | glmM | Dred_3054 | Dred_0294 | Uncharacterized P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.629 |
Dred_3054 | glmU | Dred_3054 | Dred_0099 | Uncharacterized P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.420 |
dacA | Dred_0293 | Dred_0292 | Dred_0293 | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like. | 0.991 |
dacA | glmM | Dred_0292 | Dred_0294 | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.835 |
dacA | glmS | Dred_0292 | Dred_0295 | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.436 |
glmM | Dred_0293 | Dred_0294 | Dred_0293 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like. | 0.576 |
glmM | Dred_1383 | Dred_0294 | Dred_1383 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: chy:CHY_0976 glucose-1-phosphate thymidylyltransferase. | 0.626 |
glmM | Dred_1810 | Dred_0294 | Dred_1810 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PFAM: hexokinase; KEGG: dre:406339 hexokinase 2. | 0.918 |
glmM | Dred_3054 | Dred_0294 | Dred_3054 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Uncharacterized P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities. | 0.629 |
glmM | dacA | Dred_0294 | Dred_0292 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.835 |
glmM | glmS | Dred_0294 | Dred_0295 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.990 |
glmM | glmU | Dred_0294 | Dred_0099 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.997 |
glmM | murC | Dred_0294 | Dred_0676 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.663 |
glmM | recA | Dred_0294 | Dred_1920 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.661 |