STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_0641PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: mta:Moth_0736 peptidase S1 and S6, chymotrypsin/Hap. (381 aa)    
Predicted Functional Partners:
Dred_0467
PFAM: peptidase S1 and S6, chymotrypsin/Hap; Peptidase S7, flavivirus helicase (NS3); KEGG: ttj:TTHA1320 periplasmic serine protease.
  
  
 
0.928
Dred_0758
PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: mta:Moth_0736 peptidase S1 and S6, chymotrypsin/Hap.
  
  
 
0.906
Dred_2145
KEGG: ava:Ava_4779 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.753
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.665
Dred_1339
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: lsa:LSA0513 putative stress-responsive transcriptional regulator.
  
  
 0.586
Dred_1556
GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sth:STH843 two-component sensor histidine kinase.
  
  
 0.551
Dred_0640
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: mta:Moth_2263 metal dependent phosphohydrolase.
       0.526
Dred_1730
PFAM: FAD dependent oxidoreductase; KEGG: tko:TK0122 proline dehydrogenase, beta subunit.
  
 
  0.525
lon
ATP-dependent proteinase, Serine peptidase, MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
 0.524
rplY
LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
   0.512
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.