STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_0864PFAM: DNA methylase N-4/N-6 domain protein; KEGG: sth:STH334 DNA modification methylase M.SthI; Belongs to the N(4)/N(6)-methyltransferase family. (299 aa)    
Predicted Functional Partners:
Dred_0865
KEGG: sth:STH333 restriction endonuclease R.SthI.
       0.782
Dred_0866
PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: msu:MS1646 hypothetical protein.
       0.658
Dred_1193
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mes:Meso_1200 DNA methylase N-4/N-6; Belongs to the N(4)/N(6)-methyltransferase family.
  
     0.634
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.618
Dred_0863
PFAM: phage integrase domain protein SAM domain protein; KEGG: gka:GKP13 integrase/recombinase; Belongs to the 'phage' integrase family.
       0.498
Dred_1737
KEGG: mgm:Mmc1_1358 hypothetical protein.
 
   
 0.495
Dred_2145
KEGG: ava:Ava_4779 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.494
Dred_0498
KEGG: bcl:ABC1366 hypothetical protein.
 
   
 0.462
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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