node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dred_0783 | aroA | Dred_0783 | Dred_1151 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.942 |
Dred_0783 | aroB | Dred_0783 | Dred_1021 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.813 |
Dred_0783 | aroC | Dred_0783 | Dred_1019 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
Dred_0783 | aroE | Dred_0783 | Dred_1018 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.813 |
Dred_0783 | aroK | Dred_0783 | Dred_0781 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.888 |
Dred_0783 | aroK-2 | Dred_0783 | Dred_1020 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.806 |
Dred_0783 | aroQ | Dred_0783 | Dred_1050 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.713 |
Dred_0783 | trpC | Dred_0783 | Dred_0251 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: chy:CHY_1584 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.772 |
Dred_1017 | aroB | Dred_1017 | Dred_1021 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.723 |
Dred_1017 | aroC | Dred_1017 | Dred_1019 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.759 |
Dred_1017 | aroE | Dred_1017 | Dred_1018 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.971 |
Dred_1017 | aroK | Dred_1017 | Dred_0781 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.423 |
Dred_1017 | aroK-2 | Dred_1017 | Dred_1020 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.778 |
Dred_1017 | nadD | Dred_1017 | Dred_2519 | TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: mta:Moth_1559 HAD-superfamily phosphatase subfamily IIIA. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.401 |
aroA | Dred_0783 | Dred_1151 | Dred_0783 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 0.942 |
aroA | aroB | Dred_1151 | Dred_1021 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.994 |
aroA | aroC | Dred_1151 | Dred_1019 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
aroA | aroE | Dred_1151 | Dred_1018 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.995 |
aroA | aroK | Dred_1151 | Dred_0781 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.989 |
aroA | aroK-2 | Dred_1151 | Dred_1020 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.998 |